CD 200 Is a Ligand for All Members of the Simon Wong and Philip A . Marsden
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Immunoregulatory CD 200 Is a Ligand for All Members of the Simon Wong and Philip A . Marsden
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CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules.
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. We have also cloned and sequenced a f...
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